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Recombinant Rabbit Monoclonal Antibody to CD8A (Clone : C8/1779R)
12-1048
100 ug
€818
Legenda image
Formalin-fixed, paraffin-embedded human Lymphoma stained with CD8a Rabbit Recombinant Monoclonal Antibody (C8/1779R).
Product description
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
Specifications
Applications
IHC
Host
Rabbit
Clonality
Monoclonal
Clone
C8/1779R
Isotype
Rabbit IgG
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C
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Recombinant Rabbit Monoclonal Antibody to CD8A (Clone : C8/1779R)
12-1048
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Recombinant Rabbit Monoclonal Antibody to CD8A (Clone : C8/1779R)
12-1048
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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