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Anti-Hu CD146 Purified
11-783-C100
0,1 mg
€167
Product description
CD146, also known as MCAM (melanoma cell adhesion molecule) or MUC18, is a heavily glycosylated transmembrane glycoprotein with more than 50% of the mass from carbohydrates. It is expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, activated T cells and activated keratinocytes, and on some cancer cells, especially melanoma. The presence of CD146 on circulating blood cells has been confined to the activated T cells rather than circulating endothelial cells. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration.
Specifications
Applications
FC, IP, IHC-P, IHC-Fr, WB, ICC
Host
Mouse
Clonality
Monoclonal
Clone
P1H12
Isotype
Mouse IgG1
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-Hu CD146 Purified
11-783-C100
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Anti-Hu CD146 Purified
11-783-C100
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