Toggle Nav
Anti-Hu CD120a Purified
11-773-C100
0,1 mg
€167
Product description
CD120a / TNF R1, also known as TNFR55 or TNFRSF1A, is a 55 kDa receptor for tumor necrosis factor alpha and it is expressed in most tissues. By binding its trimeric ligand the CD120a protein forms trimers and the conformation change leads to dissociation of the inhibitory factor SODD from its intracellular death domain and in formation of signaling platform. CD120a can mediate apoptosis, and function as a regulator of inflammation. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.
Specifications
Applications
FC, IP, IHC-P, IHC-Fr
Host
Mouse
Clonality
Monoclonal
Clone
H398
Isotype
Mouse IgG2a
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
Do you have any questions about this product?
Order your product by email
Productname
Anti-Hu CD120a Purified
11-773-C100
By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Request a sample
Productname
Anti-Hu CD120a Purified
11-773-C100
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Are you looking for specific products, alternatives or documentation?
