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Anti-LARGE1 Purified
11-702-C100
0,1 mg
€231
Product description
LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein alpha-dystroglycan. Mutations of LARGE1 lead to hypoglycosylation of alpha-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation. Altered alpha-dystroglycan glycosylation may also play a role in cancer, as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells.
Specifications
Applications
FC, WB
Host
Mouse
Clonality
Monoclonal
Clone
LARGE-02
Isotype
Mouse IgG2b
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-LARGE1 Purified
11-702-C100
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Anti-LARGE1 Purified
11-702-C100
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