Grb2 (growth factor receptor-bound protein 2) is a highly conserved adaptor protein composed of central SH2 domain flanked by two terminal SH3 domains. Grb2 mediates coupling of receptor protein tyrosine kinases to a guanine nucleotide exchange factor Sos, thereby enabling the tyrosine kinases to stimulate activity of Ras and hence of MAP kinase pathway. Grb2 also can bind to receptor protein tyrosine phosphatases and affect their signaling.
Productname
Anti-GRB2 Purified
11-554-C100
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Productname
Anti-GRB2 Purified
11-554-C100
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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