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Anti-SIT Purified
11-345-C100
0,1 mg
€206
Product description
SIT (SHP2-interacting transmembrane adaptor protein) is expressed exclusively in lymphoid organs and acts either as a positive or as a negative regulatory element in T cell activation and in T cell development. Binding to Grb2 plays a pivotal role in signal transduction. Hubener et al. (2001) determined that the SIT gene contains 5 exons and spans 1.8 kb of genomic DNA. The SIT promoter demonstrated strong transcriptional activity and potential binding sites for both ubiquitous and lymphoid-specific transcription factors.
Specifications
Applications
FC, IP, WB
Host
Mouse
Clonality
Monoclonal
Clone
SIT-01
Isotype
Mouse IgG1
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-SIT Purified
11-345-C100
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Anti-SIT Purified
11-345-C100
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