Product description
CD170, also known as Siglec 5 (sialic acid binding Ig-like lectin 5) is a type 1 transmembrane glycoprotein containing two cytoplasmic immunoreceptor tyrosine inhibitory motifs (ITIMs). CD170 forms homodimers and functions as an inhibitory receptor able to downregulate cell activation. It binds to alpha2,3- and alpha2,6-linked sialic acid ligands, e.g. on glycophorin A (CD235a). Aberrant expression of CD170 by CD34+ progenitor cells can be observed in case of acute myeloid leukemias.
Specifications
Applications
FC, IP, IHC-Fr, ELISA, ICC
Clonality
Monoclonal
Clone
1A5
Isotype
Mouse IgG1
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C

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Anti-Hu CD170 Purified

11-156-C100

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Anti-Hu CD170 Purified

11-156-C100

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