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Anti-Hu CD184 Purified
11-146-C100
0,1 mg
€167
Product description
CD184, also known as CXCR4 or fusin, is a receptor for the C-X-C chemokine SDF-1. It is expressed mainly in hematopoietic cells, vascular endothelium, and neural tissue. CD184 is a G-protein coupled receptor containing extracellular N-terminal, seven transmembrane domains and intracellular C-terminal domain. It transduces signal by increasing the intracellular calcium level. CD184 plays an essential role in vascularization of the gastrointestinal tract, and is involved in cerebellar development and in hematopoiesis. It is also a coreceptor (with CD4) for HIV-1 X4 virus and a primary receptor for some HIV-2 isolates.
Specifications
Applications
FC, IHC-P, ICC
Host
Mouse
Clonality
Monoclonal
Clone
12G5
Isotype
Mouse IgG2a kappa
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-Hu CD184 Purified
11-146-C100
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Anti-Hu CD184 Purified
11-146-C100
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