Adropin Polyclonal Antibody

Adropin is a 76 amino acid secreted peptide expressed in the brain, liver, and plasma and is encoded by the energy homeostasis associated gene.{16583} It is very highly conserved in mammals, and is involved in glucose homeostasis and lipid metabolism.{16583} Plasma levels of adropin decrease with age and have been associated with metabolic disorders such as dyslipidemia and insulin resistance.{21988} Adropin is involved in post-transcriptional activation of eNOS, the up-regulation of VEGFR2, and activation of the ERK1/2 pathway.{21989} Adropin’s involvement in endothelial cells results in increased proliferation and migration, and decreased permeability and apoptosis.{21989} Cayman’s Adropin Polyclonal Antibody can be used for ELISA and Western blot applications. The antibody recognizes adropin at 14-17 kDa from human samples.