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Adenosine Receptor A2A Monoclonal Antibody (Clone 7F6-G5-A2)
10011454-1
1 each
Price on request
Product description
Adenosine receptor A2A Monoclonal Antibody (A2AR) is a multi-pass membrane protein that is normally localized to the plasma membrane.{15465} This receptor is part of the G protein-coupled receptor family that binds adenosine and serves multiple functions. Antagonists of this receptor have been targeted for the treatment of Parkinson’s disease.{15466,5049} Early reports found this receptor is found primarily in the brain striatum, but is also found in immune cells and other tissues as well.{15466} A2AR is comprised of 412 amino acids with an expected molecular weight of 45 kDa.{16148,15465} However multiple glycosylation sites exist that may explain the retarded migration observed by western blotting (45-50 kDa).{15465} This antibody has been extensively characterized and the epitope has been mapped to the third intracellular loop of the receptor.{16545}
Specifications
Applications
WB
Host
Mouse
Clonality
Monoclonal
Clone
7F6-G5-A2
Isotype
IgG2a
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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Productname
Adenosine Receptor A2A Monoclonal Antibody (Clone 7F6-G5-A2)
10011454-1
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