Tyrosine Hydroxylase (Phospho-Ser31) Polyclonal Antibody

Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease, and drug abuse.{14414,14416,14417} TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signalling.{14444,14443,14439} The activity of TH is also regulated by phosphorylation.{14441,14440,14442} Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs.