Product description
GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids.{13140,13139} Found predominantly in the ?-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion.{14194,14741} Overexpression of GPR40 in mouse ? cells leads to glucose intolerance suggesting a link between GPR40 expression and diabetes.{14194,14741} The receptor has also been identified as a possible mediator of oleate- and linoleate- stimulated proliferation of the human breast cancer cell line, MCF-7.{14742,13137} GPR40 has a calculated mass of 31.4 kDa bases on its amino acid sequence.
Specifications
Applications
WB
Host
Rabbit
Clonality
Polyclonal
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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FFAR1 (GPR40) Polyclonal Antibody

10007205-1

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FFAR1 (GPR40) Polyclonal Antibody

10007205-1

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