?-3 Fatty acids, represented primarily by docosahexaenoic acid, eicosapentaenoic acid, and ?-linoleate, are essential dietary nutrients required for normal growth and development. ?-3 Arachidonic acid methyl ester is a neutral, lipid-soluble form of the rare fatty acid ?-3 arachidonic acid. The ?-3 fatty acids, as a group, are associated with decreased inflammatory and autoimmune activity, and a reduction in thrombosis and platelet activation.{5525}