DMPO

Free radicals are highly reactive, short-lived species. Spin traps react with radicals, forming stable adducts that can be further studied. DMPO is a commonly-used spin trap that reacts with O-, N-, S-, and C-centered radicals.{2717,10527,3851} This allows their characterization when used in association with electron spin resonance and immuno-spin trapping.{12375,12380,12293} DMPO is water-soluble, rapidly penetrates lipid bilayers, has low toxicity, and can be used in vitro and in vivo.{17434,9996,4914}