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Monoclonal Antibody to CD73 (Clone: ABM40E2)
10-4106
100 ug
€399
Legenda image
Immunohistochemical analysis of CD73 in renal cell carcinoma using CD73 antibody (Clone: ABM40E2) at 5 µg/ml.
Product description
CD73, also known as ecto-5'-nucleotidase, is a glycosyl-phosphatidylinositol linked plasma membrane glycoprotein that is expressed on multiple cell types and in different tissues. It is a key enzyme in the regulation of purinergic signaling and inflammatory reactions. It hydrolyzes extracellular AMP into adenosine, which dampens immune cell activation, and reduces leukocyte trafficking CD73 potently suppresses antitumor T cell responses through its ability to generate adenosine. It has also emerged as an important regulator of tissue homeostasis and pathophysiologic responses related to immunity, inflammation, pain, ischemia, tissue fibrosis and cancer.
Specifications
Applications
FC, IHC, WB
Host
Mouse
Clonality
Monoclonal
Clone
ABM40E2
Isotype
Mouse IgG2a Kappa
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C
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Monoclonal Antibody to CD73 (Clone: ABM40E2)
10-4106
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Productname
Monoclonal Antibody to CD73 (Clone: ABM40E2)
10-4106
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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