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Monoclonal Antibody to CD33(Clone: ABM29D3)
10-4064
100 ug
€205
Legenda image
Immunohistochemical analysis of CD33 in adenocarcinoma of rectum using CD33 antibody (Clone: ABM29D3) at 5 µg/ml.
Product description
CD33 is a member of the SIGLEC (Sialic Acid-Binding Ig-Like Lectin) family of receptors, and the gene comprises seven coding exons. Exon 2 encodes the canonical IgV domain, exon 4 encodes the IgC structural domain, and exons 6 and 7 encode cytosolic ITIMs (Immunotyrosine Inhibitory Motifs). CD33 acts as a cell surface antigen which is expressed on normal myeloid cells and CD34+ blasts in AML (Acute Myeloid Leukemia). The antigen serves as a target of GO (Gemtuzumab/Ozogamicin), which exerts anti-leukemic effects in refractory AML.
Specifications
Applications
FC, IHC, WB
Host
Mouse
Clonality
Monoclonal
Clone
ABM29D3
Isotype
Mouse IgG2a Kappa
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C
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Monoclonal Antibody to CD33(Clone: ABM29D3)
10-4064
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Productname
Monoclonal Antibody to CD33(Clone: ABM29D3)
10-4064
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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