RNA by Zymo Research

Discover easy-to-use RNA extraction kits, RNA cleanup kits and RNA analysis kits ideal for cDNA synthesis and RT-qPCR.

RNA Extraction kits

Discover easy-to-use RNA extraction kits for total RNA purification including small RNAs, separate fractions of RNA, or RNA in the same sample. Produce high-quality, highly concentrated, DNA-free RNA that is suitable for downstream applications such as RT-PCR, hybridization, and sequencing. Explore RNA extraction kits based on sample types, formats, and downstream applications.

Zymo Research's RNA extraction kits use robust technologies to ensure high yields of pure RNA, free of contaminants and inhibitors. The RNA extraction kits are designed for specific applications, whether that be total RNA purification including small RNAs, separate fractions of RNA, or RNA in the same sample. Pure RNA from RNA extraction kits is suitable for downstream applications such as Next-Gen Sequencing, RT-PCR, and hybridization.

All of Zymo Research's RNA extraction kits feature a novel binding buffer and innovative column technology. This binds total RNA including small or micro RNAs from any sample while eliminating contamination for DNA-free RNA.

Sample stabilization after collection is crucial to recover high-quality, total RNA. Many of Zymo Research's RNA extraction kits include DNA/RNA Shield™, a stabilization solution for nucleic acids in any biological sample. RNA is susceptible to degradation, so having a reagent that stabilizes the sample during RNA extraction is especially important. DNA/RNA Shield™ preserves the genetic integrity of samples at ambient temperatures. The reagent also completely inactivates infectious agents and is compatible with most of Zymo Research's RNA extraction kits.

The RNA extraction kits are categorized by sample types, formats, and downstream applications. Features such as CE-IVD, high-throughput, low input, microbiomics, and Proteinase K are available in the RNA extraction kits. Researchers can use RNA extraction kits to isolate RNA from sample types including fresh or frozen cells and tissues, FFPE tissues, whole blood, plasma, serum, urine, yeast, bacteria, and plant tissue. The RNA extraction kits produce highly concentrated, DNA-free RNA, suitable for downstream applications such as RT-PCR, hybridization, and sequencing.

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DNA/RNA Co-Extraction

Discover easy, reliable, and rapid DNA/RNA co-purification kits yielding high-quality total RNA, including small RNAs (17-200 nt), and genomic DNA without the use of phenol. These DNA/RNA co-extraction kits are fully compatible with downstream applications including reverse transcription, microarray, Next-Generation Sequencing, and more.

DNA/RNA co-extraction kits provide an opportunity for an all-in-one extraction. The all-in-one extraction makes it easier than ever to isolate both high-quality DNA and RNA at the same time. Zymo Research has a variety of DNA/RNA co-extraction kits for the isolation of high-quality DNA and RNA.

DNA/RNA co-extraction kits isolate both genomic DNA and total RNA including small/micro RNAs (>17 nt). The DNA/RNA co-extraction kits work for a wide variety of sample types including fresh/frozen cells and tissues, bacteria, blood, feces, FFPE tissues, insect, plant, plasma, serum, swabs, and saliva. Researchers can implement these DNA/RNA co-extraction kits to isolate down to picogram amounts of nucleic acid (single cell). It is now easier than ever to isolate samples with the innovative Zymo-Spin™ column, plate, and magnetic bead technologies depending on the downstream application.

Downstream applications such as sequencing, are powerful and prevalent tools for developing gene expression profiles. However, sequencing is still extremely vulnerable to biases. Therefore, it is imperative for sample collection and preservation to be done correctly prior to extraction. DNA/RNA Shield™ is a helpful tool to ensure everything remains intact. The DNA/RNA co-extraction kits work well with samples that are in good condition. If the samples are ready, it is easy to achieve DNA and RNA that is suitable for downstream applications. Examples of downstream applications include reverse transcription, microarrays, Next-Gen Sequencing, and more.

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RNA Cleanup

Zymo Research simplifies the process of RNA cleanup with its wide range of kits. Explore the best RNA cleanup kits for desired formats, targets, and downstream applications. The RNA cleanup kits are reliable and can effectively clean up any RNA sample for sensitive downstream applications such as RT-qPCR and Next-Gen Sequencing (NGS). Ensure high-quality, pure RNA for any experiment with Zymo Research’s RNA cleanup kits.

Zymo Research offers fast and simple RNA cleanup kits to simplify the previously difficult task of RNA extraction. The RNA cleanup kit procedure consists of three easy steps: bind, wash, and elute. These RNA cleanup and concentration kits achieve high-quality RNA in small quantities, from picograms to 1 mg. Pure and concentrated RNA can be eluted in as little as 6 µl, providing ultra-pure RNA.

With the use of a single-buffer system and Zymo-Spin column technology, the RNA cleanup kits allow recovery of total RNA (> 17 nt) or selective recovery of large RNAs (> 200 nt) and/or small RNAs (17-200 nt).

The RNA cleanup kits play a crucial role in obtaining high-quality, RT-PCR-ready, DNA-free RNA. The kits use innovative purification technologies that are effective with small input amounts of nucleic acids and low elution volumes. Furthermore, the kits can purify RNA from gels, enzymatic reactions, and impure or diluted samples.

They are ideal for cleaning and concentrating RNA samples. The kits also work with other types of nucleic acids, such as dsDNA, ssRNA, dsRNA, and ssDNA, including cDNA. The purification process removes enzymes, buffers, unincorporated nucleotides, oligos, humic acid, polyphenolics, dyes, salts, and chemicals. The RNA can then be used in downstream applications, such as hybridization, enzymatic reactions, RT-PCR, and sequencing.

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RNA Analysis

Discover Zymo’s thoroughly optimized and easy-to-use RNA Analysis Kits that are ideal for cDNA synthesis and RT-qPCR. Gene expression studies and diagnostic applications are made simple with Zymo Research’s RNA Analysis Kits. RNA-seq library prep kits contain all necessary reagents for Next-Gen Sequencing (NGS) library preparation.