Luminex

Luminex serve the needs of their customers in diverse markets including clinical diagnostics, pharmaceutical drug discovery, life science research, immunology, and personalized medicine.

The goal of Luminex is to transform global healthcare with innovative instruments and assays that deliver cost-effective, rapid results to clinicians and researchers.

“Complexitiy simplified,,

xMAP® Technology:

Open-architecture xMAP® Technology enables multiplexing of biological tests (assays), reducing time, labor, and costs over traditional methods. Systems using xMAP® Technology perform discrete assays on the surface of color-coded beads known as microspheres, which are then read in a compact analyzer. Using multiple lasers or LEDs and high-speed digital-signal processors, the analyzer reads multiplex assay results by reporting the reactions occurring on each individual microsphere particle.

Luminex uses proprietary techniques to internally color code microspheres with various fluorescent dyes. Through precise concentrations of these dyes, up to 500 distinctly colored bead sets can be created, each of which can be coupled to a target-specific molecule. These target-specific molecules may be antigens, antibodies, oligonucleotides, enzyme substrates, or receptors. After an analyte from a test sample is captured by this target-specific molecule, a reporter molecule, labeled with a different fluorescent dye, is introduced to complete the reaction on the surface of each microsphere. Then, the microspheres’ internal dyes are excited by the laser or LED, identifying the microsphere set. A second laser or LED excites the fluorescent dye on the reporter molecule. Using these signals, high-speed digital-signal processors identify each individual microsphere and quantify the amount of target molecule bound to its surface.

For further information about Luminex, please contact us.