Stimulants belong to a diverse group of psychoactive drugs whose function exerts a constant contribution to hyperactivity and impulse control. Illegal stimulant derivatives including amphetamines, arylcyclohexylamines, cathinones, cocaine/tropanes, phenethylamines, and piperazines are among the most widely abused across the US and Europe. However, the popularity of each substance, particularly in party culture settings, is frequently changing. Cayman offers more than 800 analytical standards for the identification of stimulants and is dedicated to working with the forensic community to quickly make reference standards available for new psychoactive substances (NPS).
Amphetamines
Amphetamine is a synthetic derivative of phenylethylamine, a naturally occurring substance found in chocolate, cheeses, and some wines that looks similar in structure to dopamine. The addition of a methyl group attached to the α-carbon of the phenylethylamine side chain protects amphetamine from degradation by onoamine oxidases, which enables the effects of amphetamine to persist. While variations of the amphetamine scaffold have been developed by pharmaceutical companies for treatment of ADHD, appetite suppression, or to slow the progression of Parkinson’s disease (e.g., Adderall, phentermine, and selegiline), designer drug chemists attempting to skirt DEA regulations have also made modifications to the basic amphetamine structure.
Parent compounds
| Article number | Description | Product Status |
| 27889-1 | N-Acetylmethamphetamine | Not restricted by Dutch Opium law |
| 26596-1 | α-ethyl 2C-D (hydrochloride) | Not restricted by Dutch Opium law |
| 27184-1 | N-benzyl-3,4-DMA (hydrochloride) | Not restricted by Dutch Opium law |
| 29844-1 | N-(1,4-dimethylpentyl)-3,4-DMA (hydrochloride) | Not restricted by Dutch Opium law |
| 13885-5 | DOI (hydrochloride) | Not restricted by Dutch Opium law |
| 31868-1 | Ethiopropamine (hydrochloride) | Not restricted by Dutch Opium law |
Metabolites
| Article number | Description | Product Status |
| 9001830-5 | 4-hydroxy Amphetamine (hydrochloride) | Not restricted by Dutch Opium law |
| 9002853-1 | 4-hydroxy Amphetamine Glucuronide (trifluoroacetate salt) | Not restricted by Dutch Opium law |
| 30531-1 | 3,4-Dihydroxyamphetamine (hydrochloride) | Not restricted by Dutch Opium law |
| 19208-1 | N-Formylamphetamine (CRM) | Not restricted by Dutch Opium law |
Parent compounds
| Article number | Description | Product Status |
| 27728-1 | α-Butylaminohexanophenone (hydrochloride) | Not restricted by Dutch Opium law |
| 30598-1 | α-Ethylaminohexanophenone (hydrochloride) (CRM) | Not restricted by Dutch Opium law |
| 29160-1 | 4-methyl-α-Ethylaminopentiophenone (hydrochloride) (CRM) | Not restricted by Dutch Opium law |
| 29672-1 | Eutylone (hydrochloride) (CRM) * | Not restricted by Dutch Opium law |
Metabolites
| Article number | Description | Product Status |
| 14756-1 | Mephedrone metabolite (hydrochloride) ((±)-Ephedrine stereochemistry) |
Not restricted by Dutch Opium law |
| 9001434-1 | Mephedrone metabolite (hydrochloride) ((±)-Pseudoephedrine stereochemistry) |
Not restricted by Dutch Opium law |
| 10518-1 | 3,4-Methylenedioxy Pyrovalerone metabolite 1 (hydrochloride) | Not restricted by Dutch Opium law |
Isotopically Labeled Standards
| Article number | Description | Product Status |
| 28819-100 | Butylone-d3 (hydrochloride) (CRM) | Not restricted by Dutch Opium law |
| 31629-1 | Eutylone-d5 (hydrochloride) | Not restricted by Dutch Opium law |
Sanbio BV is in possession of an opium exemption for trade-related purposes with register number 16455 07 HD.
Download the Stimulant Analytical Standards Brochure here.