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This special offer is available until June 30, 2024
Save up to 20% on Multiplex ELISA kits, Panels & Duos from Arigo
This special offer is available until June 30, 2024
Terms and Conditions:
- 20% discount is applied off list price
- Cannot be used in conjunction with any other discounted pricing or quotation
- Products from other suppliers are excluded from the offer
Arigo Smart Solutions
Arigo offers ingenious solutions encompassing both convenient antibody duo/panel options and arigoPLEX® multiplex ELISA kits. These kits showcase meticulously selected targets or indicators, guided by scientific mechanisms or pathways, providing researchers with ease of use across diverse research domains.
The antibody panels are curated based on data analysis, careful experimental considerations, and researchers' preferences. Rather than aiming to cover every possible target, they provide a focused and tailored tool for making informed interpretations about mechanisms, trends, or conclusions in research. Featured products include those targeting programmed cell death, such as cuproptosis, ferroptosis, necroptosis, and pyroptosis, as well as products addressing cell senescence, tumor microenvironment, inflammasome, and neuroinflammation.
ArigoPLEX® Multiplex ELISA Kits are innovative products enabling concurrent detection of four or eight factors. Utilizing ELISA technology on commonly used 96-well plates with only an ELISA reader required, they serve as intelligent solutions to facilitate immunology and cancer research across various areas including cytotoxicity, fibrosis, Th/Treg balance, macrophage polarization and reprogramming, and inflammation.
We celebrate the 30th anniversary of our supplier, Zymo Research, with an exclusive 20% discount on ZymoPURE products!
This special offer is available until June 30, 2024
Plasmid Purification reinvented
Empower your research with ZymoPURETM plasmid DNA purification kits. Streamlined methodology and superior technology enables unrivaled speed and performance.
At the core of the ZymoPURETM technology is a novel binding chemistry and membrane that redefines plasmid purity, reduces processing time by 9 fold and enabes > 3 mg of plasmid DNA to be eluted directly from a microcentrifuge column.
ZymoPURETM II Plasmid Purification Kits
Fastest: Simple 16-minute Midi/Maxi preps
Highest yield: Up o 3 mg from a Spin-Column
Ultra- Pure: Endotoxin-Free and Transfection ready
ZymoPURETM Plasmid Miniprep Kits
Convenient Formats: Available in Spin-Column or 96-well plate
Highest yield: Up to 10 0µg Concentrated Plasmid DNA
Transfection-Ready: Low endotoxins and Ultra-Pure
Our supplier Cayman Chemical has launched a new product: Cayman LipiDOT Strips™, a simple tool for the rapid identification of protein-lipid interactions. Researchers can screen a protein of interest against 22 biologically relevant lipids in one assay in a single day at a lower price compared with existing commercial options.
Cayman LipiDOT Strips™ are Designed to Help Researchers
- Identify one or more lipids interacting with a protein of interest
- Assess a protein's relative lipid-binding specificity
- Identify protein candidates for in-depth lipid-binding analysisids in one assay in a single day at a lower price compared with existing commercial options.
A new Tool to Study Protein-Lipid Interactions
Interactions between proteins and lipids have diverse and complex roles in various biological processes, ranging from the structure, function, and dynamics of biological membranes to host-pathogen interactions, metabolism, trafficking and localization, and cell signaling. As with more hydrophilic ligands, many proteins have lipid-binding sites and can specifically interact with lipids, which can modify the structure, conformation, and assembly of proteins to influence their recruitment, localization, and activation. Protein-lipid interactions have only been characterized for a small number of proteins, and there are likely many more lipid-binding proteins to be discovered.
A better understanding of the important roles of lipids in modulating protein function through the identification of new lipid-protein interactions would be useful in the pursuit of new therapeutic avenues.
Workflow Overview
Cayman LipiDOT Strips™ are used to identify potential interactions between a target protein and 22 different lipids arrayed as a preconfigured panel using a protein-lipid overlay assay. The workflow is similar in many ways to a Western blot. The assay is simple to perform, low cost, and can be completed in a single day. The full protocol is provided with the product information.
Figure 1. Overview of Cayman LipiDOT Strips™ workflow. Cayman LipiDOT Strips™ are compatible with detection using native proteins or epitope-tagged proteins in conjunction with primary or secondary antibody reporters. Horseradish peroxidase (HRP) is shown above as an example, which in this case requires the final addition of an HRP substrate and its conversion to a product visualized at the appropriate wavelength.
Capture a Protein-Lipid Interaction Profile with Cayman LipiDOT Strips™
Each Cayman LipiDOT Strip™ is spotted with 22 biologically relevant lipids and includes two blank (blue) spots for adding positive and negative controls. They are arranged in a 3x8 grid on a 3.175cm x 6cm supported nitrocellulose membrane.
Figure 3. Location of lipids on Cayman Chemical LipiDOT Strips™ - PIPs Plus. Phosphatidylinositol, PI ● Phosphatidylinositol-3-phosphate, PI(3)P ● Phosphatidylinositol-4-phosphate, PI(4)P ● Phosphatidylinositol-5-phosphate, PI(5)P ● Phosphatidylinositol-3,4-bisphosphate, PI(3,4)P2 ● Phosphatidylinositol-3,5-bisphosphate, PI(3,5)P2 ● Phosphatidylinositol-4,5-bisphosphate, PI(4,5)P2 ● Phosphatidylinositol-3,4,5-trisphosphate, PI(3,4,5)P3) ● Phosphatidic Acid, PA ● Phosphatidylserine, PS ● Phosphatidylethanolamine, PE ● Phosphatidylcholine, PC ● Phosphatidylglycerol, PG ● Sphingomyelin, SM ● 3-Sulfogalactosylceramide, Sulfatide ● Cardiolipin, CL ● Cholesterol, Chol ● Lysophosphatidic Acid, LPA ● Lysophosphatidylethanolamine, LPE ● Lysophosphatidylcholine, LPC ● Sphingosine-1-phosphate, S1P ● Diacylglycerol, DAG ● Blue Blank (Xylene Cyanol FF)
Figure 2. Protein-lipid interactions are identified using Cayman LipiDOT Strips™ - PIPs Plus. GST-tagged PtdIns-(4,5)-P2 binding protein was used in this experiment.
Cayman LipiDOT Strips™ Feature Lipids with Diverse Biological Roles
Cayman LipiDOT Strips™ are carefully formulated with lipids that have diverse biological roles. Cayman LipiDOT Strips™ - PIPs Plus is Cayman's first introduction in this new product group. It includes biologically relevant lipids, most of them components of cellular membranes. As such, several phospholipids and cholesterol are represented, as well as diglycerides and some sphingolipids.
Membrane phospholipids are well known for their role as the main component of membranes where they form the lipid bilayer due to their amphipathic character. Alongside cholesterol (chol), a major sterol component of mammalian cell membranes that interacts with membrane phospholipids, lipids interact with proteins to influence their behavior.
Phosphatidylinositol (PI, also known in the literature as PtdIns) is a class of membrane phospholipid that can be phosphorylated at different positions of the inositol ring to produce a variety of phosphatidylinositol (also known as phosphoinositide) phosphates (PIPs), a family of membrane lipids that act as crucial lipid signaling molecules. PIPs participate in many cellular responses by functioning as location markers, analogous to biochemical ZIP codes, organizing cellular proteins to particular sites and directing their activities through specific protein-lipid interactions. PIPs can also act as precursors for other second messengers, as, in the case of PIP2, IP3 and diacylglycerol (DAG) through hydrolysis by phospholipase C. DAG molecules act as second messengers and recruit protein kinase C (PKC), a key enzyme family with roles in many signal pathways, to cell membranes.
Other membrane lipids can also be transformed into lipid signaling molecules that control a number of downstream responses such as cell migration, proliferation, and survival. Lysoglycerophospholipids, including lysophosphatidic acid (LPA), lysophosphatidylcholine (LPC), or lysophosphatidylethanolamine (LPE) are formed by the PLA2-catalyzed hydrolysis of membrane phospholipids. The bioactive sphingolipid sphingosine-1-phosphate (S1P) is structurally similar to LPA and can also be produced at membranes by hydrolysis of sphingomyelin (SM), which results in the release of the amino alcohol sphingosine, which can then be phosphorylated by sphingosine kinase to yield S1P.
Cayman LipiDOT Strips™ - PIPs Plus also include the membrane lipids sulfatide and cardiolipin (CL). Sulfatide is a sulfated glycosphingolipid that has a prominent role in the nervous system. It is abundant in the myelin sheath, a lipid-rich extension of the plasma membrane that protects axons and assists the transmission of electrical impulses between neurons. CL is a phospholipid and a major lipid component of the inner mitochondrial membrane with roles in bioenergetics and mitochondrial dynamics.
Why Cayman LipiDOT Strips™
Cayman Chemical has made high-quality lipids available to the scientific research community for over 40 years. Cayman Chemical offer an extensive selection of biologically relevant lipids that is supported by experienced scientists with state-of-the-art analytical equipment. View Cayman Chemical's Lipid Resource Center to explore more.
High-purity lipids are the backbone of Cayman LipiDOT Strips™. Cayman Chemical's lipid experts make certain that lipids are carefully handled at every step to avoid lipid oxidation and are fully solubilized. Cayman Chemical takes these steps to ensure our assays are reliable and perform as expected.
Most lipids on the Cayman LipiDOT Strips™ are available as an individual component for purchase. These tools are invaluable for complementary methods to Cayman LipiDOT Strips™ such as liposome co-sedimentation and co-floatation assays.
Ordering information:
| Catalog Number | Description |
| #38924 | Cayman LipiDOT Strips™ - PIPs Plus |
| #39380 | Cayman LipiDOT Strips™ - Developing Chamber |
Our supplier Cayman Chemical has launched a new product: Cayman LipiDOT Strips™, a simple tool for the rapid identification of protein-lipid interactions. Researchers can screen a protein of interest against 22 biologically relevant lipids in one assay in a single day at a lower price compared with existing commercial options. Cayman LipiDOT Strips™ are Designed […]
An insight in our new supplier MedChemExpress:
MedChemExpress (MCE), located in New Jersey offer a wide range of high-quality research chemicals and biochemicals for scientific use. They have professionally experienced and friendly staff to meet your needs. MCE is a competent and trustworthy partner for your research and scientific products.
Quality
Product quality is the key to success and we take pride in offering only highest-grade products. Product identity, quality, purity and activity are assured by their robust quality control programs and procedures. MCE provide HNMR, LC-MS, HPLC, stability testing and activity assays of their products to customers.
Experience
The scientific team is highly experienced and has a successful track record in molecular synthesis. MCE is proficient in the synthesis of milligram to kilogram scale of structurally diverse and synthetically challenging molecules.
MCE is customer-oriented and work closely with the to meet their need.
Selection of MedChemExpress products
Signaling pathways
MCE offers a wide range of products that are related to several Signaling pathway, inclucing:
- Anti-infection
- Epigenetics
- Neuronal Signaling
- Apoptosis
- Autophagy
- Stem Cell/Wnt
- PROTAC
- Immunology/Inflammation; and many more.
Screening libraries
MCE can provide 170+ compound libraries which include Bioactive Sceening Libraries, Diversity Libraries and Vitual Screening Database. These libraries contain over 16 million available compounds. These compound libraries are useful professional tools for drug discovery and new indication research and can be used for HTS, high-content screening (HCS) and virtual screening (VS).
recombinant proteins
MCE offers a comprehensive catalog of recombinant proteins with excellent lot-to-lot consistency, superior activity and significantly low endotoxin levels for a variety of applications, including cell growth and differentiation, cell signaling, studies involving disease onset and progression and biopharmaceutical target discovery, protein structure and function analysis.
Products from MCE can be used in a broad range of reseach areas, such as:
- Cancer research
- Neurological Disease
- Metabolic disease
- Infection
- Cardiovascular Disease; and many more.
An insight in our new supplier MedChemExpress: MedChemExpress (MCE), located in New Jersey offer a wide range of high-quality research chemicals and biochemicals for scientific use. They have professionally experienced and friendly staff to meet your needs. MCE is a competent and trustworthy partner for your research and scientific products. Quality Product quality is the […]
Stockholm, 11 September 2023
Established in 1997, Nordic BioSite was founded with the ambition to be the leading Nordic distribution partner of premium reagents for life science research use. Four years ago, following the successful penetration of the Nordic market, their commercial ambition was broadened to become the leading life science distributor in Europe. Nordic BioSite Group has since increased sales x5 through high organic growth and yearly best-inclass acquisitions.
Today we are delighted to announce our latest acquisition, LubioScience, in Switzerland. As the fastest growing life science distributor in Switzerland, LubioScience is an excellent addition to our Group and an important step towards our ambition to provide exceptional distribution services across Europe.
In recognition of our geographical expansion, we are ready to progress to a new name that is more reflective of our growth and future ambitions. Effective from today, Nordic BioSite Group will be known as Europa Biosite. Europa Biosite is a name that reflects our aspirations to be the leading site for life science products within Europe. Looking to the future, we aspire to further develop our success across Europe through additional industry-leading acquisitions and continued high organic growth. New website to be launched October 2023.
“Switzerland is a key research hub in Europe and hence we have been eager to be present there to help existing and new suppliers gain access to this fast-growing market. LubioScience has been #1 on our target list for a long time as we have been impressed with the success they have had in the Swiss market. I am sure there are many things we can learn from their success to replicate within the Group, just like we can transfer our commercial and operational best practices to LubioScience” says CEO Sune Schmolker.
Dr. Tobias Dietschy and Dr. Daniel Auerbach will continue working at LubioScience, and comment in a shared statement on the deal: “The consolidation of the European life science distribution market will generate value for suppliers and customers, and we see an exciting future for LubioScience as part of the fastest growing pan-European group of distributors within our industry”.
The parties have chosen not to disclose the financial terms of the transaction.
For further information:
Europa Biosite: Sune Schmolker, CEO, sune.schmolker@nordicbiosite.com, +45 42 92 17 79
LubioScience: Tobias Dietschy, tobias.dietschy@lubio.ch, + 41 76 559 45 67
About LubioScience
LubioScience has been a leading distributor of life science products for over 20 years in its home market, Switzerland. Its highly qualified employees support local customers in gaining access to innovative products from top quality global life
science manufacturers. For further information please visit https://www.lubio.ch.
About Europa Biosite
Europa Biosite is a European supplier of life science products and services. We are a group of five leading distribution companies: Biomol in Germany, Cambridge Bioscience in the UK and Ireland, Nordic BioSite in the Nordics and Baltics,
Sanbio in Benelux and Szabo-Scandic in Austria. The group has a portiolio of over 5 million products, representation in 15 European countries and a highly skilled team of over 130 employees.
Stockholm, 11 September 2023 Established in 1997, Nordic BioSite was founded with the ambition to be the leading Nordic distribution partner of premium reagents for life science research use. Four years ago, following the successful penetration of the Nordic market, their commercial ambition was broadened to become the leading life science distributor in Europe. […]
The extensive range of ELISA and assay kits of our suplier LS Bio enable quantitative and qualitative monitoring of a variety of biological processes, including cell proliferation, oxidative stress, apoptosis, signaling pathways, and more. Each kit includes all necessary reagents and is rigorously tested to ensure precision, accuracy, sensitivity, specificity, and reproducibility.
ELISA (enzyme-linked immunosorbent assay) kits are a quick, convenient and accurate research tool for the detection and quantitation of targets of interest in cultures and samples. LS Bio offers more than 50,000 cost-effective, ready-to-use ELISA kits for thousands of targets of interest. Each kit includes all necessary reagents, as well as a clear protocol that walks you through the entire process, from sample preparation to result analysis.
Traditional ELISA Kits
Direct, sandwich and competition ELISA kits for the quantitative or qualitative detection of specific antigens in a variety of sample types.
Cell-Based ELISA Kits
Fast and cost-effective way to quantify specific target antigens in vitro.
DNA-Binding ELISA Kits
Quickly and easily detect active transcription factors in eukaryotic nuclear extracts or cell lysates without the use of harmful radioactive reagents.
Phospho-Specific ELISA Kits
For the specific detection of phosphorylated target proteins.
ELISA development kits allow researchers to prepare their own ELISA plates as needed, at a lower cost per plate than off-the-shelf kits. Each ELISA development kit includes the four principal components required to assemble and run a sensitive and specific sandwich ELISA: the capture and detection antibody pair, antigen standard, and conjugate. LS Bio also supplies all other ancillary products needed, such as plates, wash buffers, diluents, secondary detection antibodies, substrates, and stop solutions.
Chemiluminescent Immunoassay (CLIA) Kits
CLIA offers significant advantages over traditional assay detection methods, eliminating messy isotopic detection or chromogens that require absorption spectroscopy, in favor of chemical reactions that produce light. Extraordinary sensitivity, low background, a wide dynamic range, and inexpensive instrumentation distinguish luminometry from other analytical methods.
Other Functional Assays
Ready-to-use kits that incorporate non-ELISA technologies to monitor a variety of biological processes. Assay kits are available for monitoring cell proliferation, cell damage, oxidative stress, cytotoxicity, apoptosis, metabolism, signaling pathways, signal transduction, and more.
| Assay Kit | Species | Catalog Number |
| CD9 ELISA Kit | Human | LS-F6853 |
| GABA/Gamma-Aminobutyric Acid ELISA Kit | All | LS-F4121 |
| HAMP/Hepcidin ELISA Kit | Mouse | LS-F11620 |
| His Tag ELISA Kit | All | LS-F55748 |
| HMG1/HMGB1 ELISA Kit | Mouse | LS-F23080 |
| IFNA/Interferon Alpha ELISA Kit | Rat | LS-F4130 |
| IFNB/Interferon Beta ELISA Kit | Dog | LS-F6086 |
| Lipopolysaccharide/LPS ELISA Kit | All | LS-F17912 |
| PYCARD/ASC/TMS1 ELISA Kit | Human | LS-F19843 |
| TNNI3/Cardiac Troponin I ELISA Kit | Mouse | LS-F24180 |
| TPSAB1/Mast Cell Tryptase ELISA Kit | Human | LS-F13484 |
| Trypsin ELISA Kit | Pig | LS-F6198 |
| TTR/Transthyretin ELISA Kit | Monkey | LS-F49258 |
Please contact us for more information support@sanbio.nl or place order through orders@sanbio.nl
The extensive range of ELISA and assay kits of our suplier LS Bio enable quantitative and qualitative monitoring of a variety of biological processes, including cell proliferation, oxidative stress, apoptosis, signaling pathways, and more. Each kit includes all necessary reagents and is rigorously tested to ensure precision, accuracy, sensitivity, specificity, and reproducibility. ELISA Kits ELISA […]
The Quick-16S Plus NGS Library Prep Kit (V3-V4, UDI) is the fastest and simplest NGS library prep targeting the V3-V4 region of the 16S rRNA gene for high-throughput sequencing. The automation-friendly protocol utilizes a single qPCR/PCR for combined targeted amplification and barcode addition using specially designed primers. After pooling by equal volume, a single clean-up of the final library is performed, rather than massive AMPure® bead-based clean-ups. Additional library quantification analysis such as TapeStation® analysis or gel electrophoresis are not necessary. With these features, the workflow dramatically reduces the hands-on time of library preparation to only 30 minutes.
Highlights for Quick-16S Plus NGS Library Prep Kit (V3-V4, UDI):
• The most streamlined NGS kit with only 30 minutes of hands-on time for 96 samples.
• 100% automation ready with only a single PCR step and without the need for normalization.
• Real-time PCR enables absolute microbial copy number quantification.
Ordering information:
| Catalog Number | Description |
| D6421-PS1 | Quick-16S Plus NGS Library Prep Kit (V3-V4 UDI) with Primer Set 1 |
| D6421-PS2 | Quick-16S Plus NGS Library Prep Kit (V3-V4 UDI) with Primer Set 2 |
| D6421-PS3 | Quick-16S Plus NGS Library Prep Kit (V3-V4 UDI) with Primer Set 3 |
| D6421-PS4 | Quick-16S Plus NGS Library Prep Kit (V3-V4 UDI) with Primer Set 4 |
| D6421-PS5 | Quick-16S Plus NGS Library Prep Kit (V3-V4 UDI) with Primer Set 5 |
| D6421-PS6 | Quick-16S Plus NGS Library Prep Kit (V3-V4 UDI) with Primer Set 6 |
| D6421-PS7 | Quick-16S Plus NGS Library Prep Kit (V3-V4 UDI) with Primer Set 7 |
| D6421-PS8 | Quick-16S Plus NGS Library Prep Kit (V3-V4 UDI) with Primer Set 8 |
Matreya LLC, Lipids and Biochemicals, a Cayman Chemical Company
Our supplier Cayman Chemical is known for their high quality biochemicals, assay kits, antibodies, and recombinant proteins and offer contract services for custom synthesis/analysis, assay development/screening, and drug discovery.
Their mission is to help make research possible. Therefore they continuously adding new (developed) products to their portfolio. Some of the products they have recently added are a broad range of Antibodies for glycolipids, Bacterial tetraethers, Ceramides and digydroceramides, D9 Glycolipids, Enzyme inhibitors for glycolipids, Fatty acids and methyl esters, Fluorescent standards, Gangliosides, Glycosyl Glycerides, Glycosphingolipids, Lipid mixtures, Plant sterols and steryl glucosides, Phospholipids, Phosphosphingolipids, Spingosines, Stable isotype labeled standards and Ocopherols and tocotrienols.
Antibodies for glycolipids
The antibodies are directed against the carbohydrate chains of ganglioside and globoside glycolipids. The same carbohydrate moieties are found on many glycoproteins. All antibodies are quality tested by actual ELISA and TLC immunoblotting analysis.
Bacterial tetraethers
Tetraether monosaccharide phospholipids (MPL) are the main phospholipids of Thermoplasma acidophilum. They contain a glycerophosphate and a gulosyl pyranoside monosaccharide linked via a tetraether chain. MPL is useful for making liposomes to study various molecular functions.
Ceramides and digydroceramides
Ceramides and their saturated analogs dihydroceramides exert numerous biological effects including induction of cell maturation, cell cycle arrest, terminal cell differentiation, cell senescence, cell death, skin water-barrier function and protein regulation. These ubiquitous lipids can be used as standards for the analysis of tissues and identification and quantitation of major sphingolipids
Products:
Ceramides
Sphingosine
Enzyme inhibitors for glycolipids
Cayman Chemical offers inhibitors that will stop the enzymatic metabolism of glycolipids at various points in their biosynthetic routes. These include glucosylceramide synthase inhibitors PDMP and PPMP, Protein kinase C inhibitor Safingol, Acid and alkaline ceramidase inhibitors NOE and D-MAPP, and glucosidase inhibitor Conduritol B epoxide.
Products:
18624
10005276
17236
10005278
24525
24524
22676
10178
22677
24526
Fatty acids and methyl esters
Cayman Chemical offers a vast array of very high purity fatty acids and fatty acid methyl esters including saturated, polyunsaturated, trans-unsaturated, conjugated linoleic, conjugated linolenic, 2-hydroxy, 3-hydroxy, omega-hydroxy, branched methyl, and cyclopropyl. Many of these fatty acids have powerful biological effects.
Simply fatty acids and methyl esters
Conjugated linoleic Acids (VLA) and Methyl Esters
90140
31552
24581
90370
24580
24582
24583
90145
24584
Conjugated linolenic Acids (VLA) and Methyl Esters
24807
27098
10008333
Hydroxy Fatty Acids and Methyl Esters
2-hydroxy fatty acids and methyl esters
22678
24585
24586
24587
90390
24588
22679
24589
24590
24591
24592
24593
24594
24595
24597
24598
24599
24658
22680
3-hydroxy fatty acids and methyl esters
24607
24608
24609
24610
24611
24612
24613
24614
24640
24641
24642
24643
22689
24644
16871
24645
20108
28735
24646
22692
24647
Omega hydroxy fatty acids and methyl esters
24648
24649
24650
24651
24652
24653
24654
24655
24656
24657
Branched and Cyclic Fatty Acids and Methyl Esters
24809
24810
24812
24814
24816
24817
24819
24820
24821
24822
24823
24824
24825
26735
26736
Quantitative Fatty Acid Methyl Ester (FAME) Mixtures
298365
28665
28666
29366
28668
28669
28670
28645
28646
29352
29353
29354
28650
28651
29356
29357
29367
29368
29374
29375
29376
29377
24658
29370
29334
29335
29369
29336
Qualitative Fatty Acid Methyl Ester (FAME) Mixtures
28682
28681
28661
28662
28663
28683
29373
28679
28680
29363
29358
29359
29360
29361
29362
Fluorescent standards
Their fluorescent standards that can be detected in cultures and in biological systems, making them ideal for studies involving the metabolism of sphingolipids. These lipid analogs are very useful for determining the localization of various sphingolipids in membranes and organelles. The NBD fluorescent group attached to hexanoic acid has been shown to be readily taken up by cells and used in the biosynthesis of more complex sphingolipids.(Lipsky and Pagano J Cell Biol 1985)
Products:
24439
24330
24440
24441
24326
24327
24328
22830
22851
23209
24627
22828
22829
24628
33799
24470
Gangliosides
Gangliosides are acidic glycosphingolipids participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis, and metastasis. Cayman Chemical offers a number of high purity deuterated gangliosides which are ideal for mass spectrometry studies.
Products:
15586
24629
24837
24839
24840
33799
24838
31710
24849
31711
24850
31590
33263
24851
31591
31708
25487
31709
24852
31712
31561
24856
24857
29359
29362
29361
29362
33073
31195
31196
31198
31549
31551
31707
31593
31592
31562
34605
34778
15588
27202
Glycosyl Glycerides
Monogalactosyldiglyceride (MGDG) and digalactosyldiglyceride (DGDG) are two important biomolecules that are especially prevalent in chloroplast membranes and photosynthetic tissues, including those of algae and some bacteria. A proper ratio of MGDG and DGDG is critical for membrane function. MGDG plays an important role in the organization and activity of the embedded protein supercomplexes of the thylalkoid membrane of photosystem II and it helps to maintain an optimum lipid to protein ratio. DGDG forms a lipid bilayer in the lipid membrane whereas MGDG does not.
Glycosphingolipids
Glycosphingolipids affect apoptosis, cell proliferation, endocytosis, intracellular transport, cell migration and senescence, and inflammation. Cayman Chemical produces galactosylceramides, glucosylceramides, sulfatides (sulfo-galactosylceramides), lactosylceramides, globotriaosylceramides (ceramide trihexosides), globosides, and gangliosides. Each of these are available with natural fatty acids as well as with specific well-defined fatty acids in the ceramide moiety
Products:
Galactosylceramide
Glucosyl
Sulfatide
Lactosylceramide
Trilhexosides
Globoside
Ganglioside
Lipid mixtures
Benefits of knowing the fatty acid content of bacteria include understanding microbes and animal nutrition. Microbial fatty acid profiles are unique from one species to another and can therefore be used in the determination of bacterial identity. Cayman offers a wide selection of fatty acid methyl ester and glycosphingolipid mixtures. Each methyl ester mixture is carefully prepared by weight and the composition is verified by gas chromatography and TLC.
Products:
29365
28665
28666
29366
28668
28669
28670
Biochemical Research standard mixes
Products:
29374
29375
29376
29377
Carbohydrate mixtures
Products:
29367
29368
Food industry Mixtures
Products:
29371
29334
29335
29369
29336
GLC standard mixtures
Products:
28645
28646
29352
29353
29354
28650
29355
29356
29357
29372
Glycosphingolipid reference mixture for TLC
Products:
29358
29359
29360
29361
29362
24856
24857
Microbiology standards
Products:
28682
28681
Products:
29372
29373
Polyunsaturated fatty acid methyl ester mixtures
Products:
28661
28662
28663
Water soluble fatty acid mixtures
Plant sterols and steryl glucosides
Cayman Chemical offers a line of cholesterols, phytosterols, and steryl glucosides which comprise an important lipid category of cholestane derivatives. Plant sterols will complex with glycosphingolipids in raft-like sub-domains and can affect many cellular functions including membrane fluidity, permeability, activity of membrane-bound enzymes, cellular differentiation, cellular signaling, and cellular proliferation.
Phospholipids
Phospholipids are well known for their role as the main component of membranes, but are also important as cellular messengers, enzyme activators, and more. Hundreds of different phospholipid molecular species are present in cells, each having variations in their phospholipid head-group or acyl tails that give them unique properties. Cayman Chemical offers an extensive list of highly purified natural and synthetic phospholipids including phosphatidylcholine, phosphatidic acid, phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, phosphatidylglycerol, and phosphosphingolipids.
Products:
Natural phospholipids
24343
24370
24331
24341
33671
24523
24344
24332
16878
Spingosines
Sphingolipids are widely distributed in animal and plant tissues, particularly in cell membranes where they serve numerous vital cellular functions. Cayman Chemical offers several isomers of sphingosine as well as a number of sphingosines with various chain lengths, deuterium labels, and fluorescence probes.
Products:
24371
26893
24373
24371
18624
24374
24375
24367
24376
22509
24378
24380
24381
22824
24384
20217
28933
28934
29919
27199
22827
9003465
24385
Stable isotype labeled standards
Stable isotope standards can be easily detected by mass spectrometry while demonstrating nearly identical physical properties to natural sphingolipids. This is very important to ensure similar extraction properties and signal response between the analytes and the internal standards.
Products:
24371
24396
24423
24452
9003461
24467
24621
24624
24625
24626
24839
24849
24850
24852
24464
31195
31196
31198
9003460
9003462
9003463
Ocopherols and tocotrienols (Vitamin E)
Vitamin E has become well known for its role as an antioxidant, in lowering levels of cholesterol and other lipids, as a neuroprotective and anti-cancer agent, and in cardiovascular disease protection. It consists of four tocopherols and four tocotrienols which have important and far-reaching biological activities. These essential lipids contain a common chromanol ring and either a saturated (tocopherol) or unsaturated (tocotrienol) side chain.
Tocopherols
26758
27193
31589
27194
27195
Tocotrienols
10008377
9001533
10008494
10008513
Flow Cytometry Panel + FlexAble
Try FlexAble for free when you purchase a Flow Cytometry Panel!
Buy any Flow Cytometry Panel and get any 10rxn size CoraLite® Plus 555 FlexAble Antibody Labeling Kit for free!
Use code FLXPNL23 on your order. Valid until Dec 31st.
Flow Cytometry Panels |
CoraLite® Plus 555 FlexAble Antibody Labeling Kits |
| Human B Cell Basics Panel | FlexAble CoraLite® Plus 555 Antibody Labeling Kit for Mouse IgG1 |
| Human Monocyte Basics Panel | FlexAble CoraLite® Plus 555 Antibody Labeling Kit for Mouse IgG2a |
| Human Naive/Memory T Cell Panel | FlexAble CoraLite® Plus 555 Antibody Labeling Kit for Mouse IgG2b |
| Human NK Cell Basics Panel | FlexAble CoraLite® Plus 555 Antibody Labeling Kit for Rabbit IgG |
| Human T Cell Basics Panel | |
| Human TBNK Basics Panel |
Hycult Biotech is happy to introduce their new and unique blocking antibody targeting complement rat C5, now available for preclinical research in rat models!
This new antibody recognizes human, rabbit and rat complement C5. It acts as an equivalent of Eculizumab and recognizes human and rabbit C5. However the affinity for rat C5 is even stronger.
The antibody recognizes intact alpha chain and binds to an epitope distinct from Eculizumab. In haemolytic assays the antibody shows efficient inhibition of alternative pathway as well as classical pathway.
This is successfully demonstrated in a rat prophylactic Myastenia gravis model in which animals were protected from disease and for destruction of the muscle endplates.
Ordering information:
Name: Rat C5, Monoclonal Antibody, clone 4G2, cat.# HM3044
Available in sizes: 20 µg,100 µg, 500 µg, 1 mg, 5 mg, and 10 mg
Applications: ELISA, Western Blotting, Functional Studies
Hycult Biotech is happy to introduce their new and unique blocking antibody targeting complement rat C5, now available for preclinical research in rat models! This new antibody recognizes human, rabbit and rat complement C5. It acts as an equivalent of Eculizumab and recognizes human and rabbit C5. However the affinity for rat C5 is even […]
The Zymo-Seq™ miRNA Library Kit is an innovative small RNA sequencing library prep kit that uses a single-adapter and circularization strategy to reduce ligation bias and provide accurate small RNA profiling from cell-free RNA (cfRNA) and total RNA. This simple, streamlined workflow minimizes hands-on time and uses gel-free removal of adapter dimers to generate stranded small RNA libraries from plasma, biofluids, cells, tissues, and more.
To prepare Zymo-Seq™ miRNA libraries, RNA is ligated to the single miRNA adapter and the ligated product is circularized. Excess adapter is blocked and removed with specialized magnetic beads that allow a completely gel-free workflow for input as low as 1 ng. The circularized miRNA-adapter product is then reverse transcribed. The resulting cDNA is amplified using Indexing PCR primers which add on Illumina-compatible adapter and unique dual index (UDI) sequences for cost-effective multiplexing. Everything needed to make sequencing-ready libraries, including indexing primers and SPRI beads, are included in the kit. It’s RNA-Seq made simple.
Highlights for Zymo-Seq miRNA Library Kit (R3006, R3007):
- Accurate miRNA profiling: A unique single adapter and circularization strategy reduces ligation bias and increases miRNA detection.
- Direct detection: Generates small RNA libraries without the need for small RNA enrichment.
- Gel-Free: Removes adapter dimers from any input without lengthy gel excision.
Ordering Information:
| Catalog number | Description |
| R3006 | Zymo-Seq miRNA Library Kit (12 preps) |
| R3007 | Zymo-Seq miRNA Library Kit (96 preps) |
The Zymo-Seq™ miRNA Library Kit is an innovative small RNA sequencing library prep kit that uses a single-adapter and circularization strategy to reduce ligation bias and provide accurate small RNA profiling from cell-free RNA (cfRNA) and total RNA. This simple, streamlined workflow minimizes hands-on time and uses gel-free removal of adapter dimers to generate stranded […]