Product description
CD49f is the 125 kDa integrin ?6 chain which associates noncovalently with the integrin ?1 subunit (CD29) and with the integrin ?4 (CD104) chain to form, respectively, the very late antigen-6 (VLA-6) and ?6?4 integrin heterodimers. VLA-6 is expressed on thymocytes, T lymphocytes, monocytes, and platelets. CD49f/CD29 expression is upregulated on activated T lymphocytes and memory T cells. VLA-6 serves as the laminin receptor on platelets, monocytes, and T cells. VLA-6-mediated binding to laminin provides a costimulatory signal to T cells for activation and proliferation.
Specifications
Applications
FC, IHC
Host
Mouse
Clonality
Monoclonal
Clone
4F10
Isotype
IgG2b
Supplier
Southern Biotech
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
2-8°C

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Mouse Anti-Human CD49f-FITC

9650-02

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Mouse Anti-Human CD49f-FITC

9650-02

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