2'-Deoxyguanosine is a purine nucleoside with diverse biological activities.{53664,53663,53662,53665} It inhibits the clonogenic growth of HL-60 and K562 leukemia cells (IC50s = 80 and 100 uM, respectively).{53664} 2'-Deoxyguanosine inhibits the growth of MOLT-4 T cells and MGL-8 B cells by 99.8 and 68.3%, respectively, when used at a concentration of 50 uM.{53663} It increases the number of binucleated cells, a marker of inhibited cytokinesis, in A. sativum meristems.{53662} 2'-Deoxyguanosine (>1 uM) also induces relaxation of precontracted isolated bovine lingual artery.{53665}
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Cayman Chemical
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