Product description
In the chicken, the CD8 molecule is present in two forms - (i) a homodimer of two ? chains and (ii) a heterodimer of an ? chain and a ? chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8?- and CD8?-chains, a relatively large proportion of the CD8+ TCR-?? cells in the spleens of embryos and young chicks express only the ?-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCR-?? CD8?? cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. The monoclonal antibody EP42 recognizes the CD8? chain.
Specifications
Applications
FC, IP, IHC
Host
Mouse
Clonality
Monoclonal
Clone
EP42
Isotype
IgG2a
Supplier
Southern Biotech
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
2-8°C

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Mouse Anti-Chicken CD8b-UNLB

8280-01

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Mouse Anti-Chicken CD8b-UNLB

8280-01

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