Rosiglitazone
A PPAR? agonist; activates PPAR?1 and PPAR?2 in reporter assays (EC50s = 30 and 100 nM, respectively); selectively activates chimeras containing the LBDs of PPAR? over PPAR? and PPAR? in a cell-based reporter assay at 10 mM; an inhibitor of ACSL4 (IC50 = 0.5 µM), inhibits RSL3-induced ferroptosis in Pfa1 cells and Pparg KO cells, and increases survival in a Gpx4 KO mouse model of ferroptosis at 0.0125 mg/ml in the drinking water; decreases HbA1c and fasting blood glucose levels in a rat model of type 2 diabetes induced by STZ and a high-carbohydrate and high-fat diet at 4 mg/kg
Do you have any questions about this product?
Order your product by email
Productname
Rosiglitazone
71740-10
By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Request a sample
Productname
Rosiglitazone
71740-10
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Are you looking for specific products, alternatives or documentation?
