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Plakophilin 3 is seen in most desmosomes and partly dispersed in cytoplasm under various fixation conditions (FA, MeAc long, MeAc short):
Positive tissues and culture cells:
stratified squamous epithelia: palmar, epidermis, scalp skin
stratified epithelia: tongue, vagina, esophagus
transitional epithelia: bladder
non-stratified epithelia: colon, duodenum, pancreas, several glands
non-epithelial: reticulum cells of lymph node follicle
HaCaT, MCF7, HeLa, HT-29, CaCo 2, Caski, BMGE, MDCK and other
Negative tissues and cell lines:
liver, heart, skeletal muscle, endothelia (vessels)
PLC, RD, SV80, HL60, Raji, Jok1, Glioma, K562, 3T3L1, A6, PtK2
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