HCC 5.1 allows detection of native complement component C5 and discrimination from activated C5b-9 complexes, especially in different forms of glomerulonephritis.
Polypeptide reacting: Mr 200,000 polypeptide of native complement component C5.
Disorders specifically detected: HCC 5.1 reacts with native C5 as ell as with C5b. Native C5 is only detected with HCC 5.1, while C5b is detected by both HCC 5.1 and HCC 5.2.