Antibody recognizes desmoglein 2 present in all epithelia and in tumors derived therefrom as well as in heart muscle and dendritic reticulum cells of lymphatic follicles. In basal epithelial cells desmoglein 2 expression is generally very low.
Polypeptide reacting: Desmoglein 2 (1069aa; calculated mol. wt. 116,760)
Reactivity on cultured cell lines: Many, including CaCo-2, HaCaT, MCF-7.