PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and 'de novo' pathways.{939} It is a potent mediator of neutrophil migration,{1437} and the production of reactive oxygen species, and IL-6 in human macrophages.{367,2296} It is a more potent mediator of platelet aggregation than PAF C-18.{3786} Pathological processes involving PAF include necrotizing enterocolitis,{5841} inflammation, asthma, and allergy.{303}
1 mg
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Cayman Chemical
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