Cayman’s STAT3 Transcription Factor Assay Kit is a non-radioactive, sensitive method for detecting specific STAT3 DNA binding activity in nuclear extracts. As an alternative to the cumbersome electrophoretic mobility shift assay (EMSA) or the lower throughput ChIP assay, this ELISA is extremely easy to perform. This kit is an ideal way to measure STAT3 transcriptional activity downstream of cytokine or drug treatment and manipulation of cells in vitro or in vivo. Cayman’s STAT3 Transcription Factor Assay Kit detects human, mouse, rat, and non-human primate STAT3 binding on the DNA target sequence. It does not cross react with other STAT transcription factors.