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Citrullinated Histone H3 (Clone 11D3) ELISA Kit
501620-96
96 Well
€705
Product description
Histone H3 is citrullinated by peptidylarginine deiminase 4 (PAD4) at residues R2, R8, and R17 during the processes of epigenetic chromatin remodeling and neutrophil extracellular trap (NET) formation. In vitro, citrullinated H3 (CitH3) is released from neutrophils that have been stimulated with calcium ionophore during the process of NETosis, and can be freed from NETs by treatment with nuclease. The measurement of CitH3, either in cell lysates or released during NETosis can be used as a functional readout of pharmacological PAD inhibition.
Specifications
Clone
11D3
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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Citrullinated Histone H3 (Clone 11D3) ELISA Kit
501620-96
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Citrullinated Histone H3 (Clone 11D3) ELISA Kit
501620-96
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