Product description
1-O-Acetylbritannilactone is a sesquiterpene lactone that has been found in I. britannica and has diverse biological activities.{60843,60844} It inhibits LPS-induced production of prostaglandin E2 (PGE2; Item No. 14010) and nuclear translocation of NF-kB in primary rat aorta vascular smooth muscle cells (VSMCs).{60843} 1-O-Acetylbritannilactone (5 and 10 µM) inhibits VEGF-induced capillary tube formation in human umbilical vein endothelial cells (HUVECs).{60844} It reduces tumor growth in an A549 mouse xenograft model when administered at a dose of 12 mg/kg per day.
Specifications
CAS number
33627-41-7
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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1-O-Acetylbritannilactone

35137-10

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1-O-Acetylbritannilactone

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