Product description
(+-)-6-Prenylnaringenin ((+-)-6-PN) is a flavonoid that has been found in the hop plant, H. lupulus, and has diverse biological activities.{64052,64054} It inhibits the T-type voltage-gated calcium (Cav) channel Cav3.2 and high-voltage-activated calcium currents in whole-cell patch-clamp assays using HEK293 cells (IC50s = 0.912 and 4.765 µM, respectively).{64052} It inhibits proliferation of PC3 and DU145 prostate cancer cells (IC50s = 18.4 and 29.1 µM, respectively).{64054} (+-)-6-PN (20 and 30 mg/kg) reduces mechanical allodynia in a mouse model of neuropathic pain induced by partial sciatic nerve ligation.{64052}
Specifications
CAS number
68682-01-9
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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