9-OxoODE-d3

9-OxoODE-d3 contains three deuterium atoms at the 10, 12, and 13 positions. It is intended for use as an internal standard for the quantification of 9-OxoODE by GC- or LC-mass spectrometry. 9-OxoODE results from oxidation of the allylic hydroxyl of either 9(S)- or 9(R)-HODE. Rabbit reticulocyte plasma and mitochondrial membranes contain both 9- and 13-oxoODEs, representing about 2% of the total linoleate residues in the membranes. Most of these oxidized linoleate residues are esterified to membrane lipids.{2262,2326,2261}