7-Methoxyflavone

7-Methoxyflavone is a flavone that has been found in Z. brasiliensis and has diverse biological activities.{57534,57539,57540,57536} It inhibits aromatase (IC50 = 1.9 µM in a cell-free assay) and LPS-induced nitric oxide (NO) production by 17.74% in RAW 264.7 macrophages when used at a concentration of 20 µM.{57534,57539} 7-Methoxyflavone activates androgen and/or glucocorticoid receptor transcriptional activity in a reporter assay and has antinociceptive effects in the acetic acid-induced writhing test in mice (ED50 = 82.5 µmol/kg).{57540,57536}