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(+-)11-HDHA
33450-25
25 ug
€95
Product description
(+-)11-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.{7479,7491} It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.{7480,7490,7492} DHA is metabolized to 11(S)-HDHA by human platelets and canine retina.{7483,7486,7484,7492} In addition to 11(S)-HDHA, 14(S)-HDHA is also produced by platelets.{7483,7484,7492} 11(S)-HDHA was shown to be an inhibitor of U-46619-induced human platelet aggregation and rabbit and rat aortic smooth muscle contraction with IC50 values of about 50, 4.7, and 7.5 µM, respectively.{7484,7481} (+-)11-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
Specifications
CAS number
87018-59-5
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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(+-)11-HDHA
33450-25
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