10-deacetyl-7-xylosyl Paclitaxel

10-deactyl-7-xylosyl Paclitaxel is a disruptor of microtubules and derivative of paclitaxel (Item No. 10461) that has been found in T. chinensis.{37074,57371} It induces the disassembly of pig brain and Physarum microtubules in cell-free assays (IC50s = 0.3 and 0.5 µM, respectively).{37074} 10-deactyl-7-xylosyl Paclitaxel inhibits proliferation of (IC50 = 5 µM), as well as induces cell cycle arrest at the G2/M phase and apoptosis in, PC3 prostate cancer cells.{57371}