Product description
(S)-WAY-100135 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT1A (IC50 = 15.5 nM in a radioligand binding assay using rat hippocampus).{58220} It is selective for 5-HT1A over 5-HT1B, 5-HT1C, and 5-HT2 receptors, as well as dopamine D1 and D2, and a1-, a2-, and B-adrenergic receptors (IC50s = >1 µM for all).{58219} (S)-WAY-100135 (10 mg/kg) increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity.{58219}
Specifications
CAS number
149007-54-5
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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(S)-WAY-100135 (hydrochloride)

32851-5

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(S)-WAY-100135 (hydrochloride)

32851-5

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