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15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2a
32791-1
1 mg
€119
Product description
15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2a (15-(6-nitroxyhexanoyl)-17-phenyl trinor PGF2a) is a nitric oxide-donating derivative of 17-phenyl trinor PGF2a (Item No. 16810).{62159} It increases cGMP levels in rabbit aqueous humor and iris ciliary body when topically administered at a concentration of 0.042%. Topical administration of 15-(6-nitroxylhexanoyl)-17-phenyl trinor PGF2a (0.14%) reduces intraocular hypertension (IOP) in a rabbit model of hypertonic saline-induced transient ocular pressure. It also reduces IOP in a cynomolgus monkey model of laser-induced ocular hypertension when administered topically at a concentration of 0.042%.
Specifications
CAS number
1194396-71-8
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2a
32791-1
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15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2a
32791-1
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