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5-Butyl-4-phenyl-6-[4-(phenylmethoxy)phenyl]-2-pyrimidinamine
31337-1
1 mg
€160
Product description
5-Butyl-4-phenyl-6-[4-(phenylmethoxy)phenyl]-2-pyrimidinamine is an inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1; IC50s = 117 and 60 nM for the human and mouse enzymes, respectively).{52747} It inhibits LPS-induced prostaglandin E2 (PGE2; Item No. 14010) production in mouse peritoneal cells (IC50 = 31 nM). In vivo, 5-Butyl-4-phenyl-6-[4-(phenylmethoxy)phenyl]-2-pyrimidinamine (25 mg/kg) reduces carrageenan-induced paw edema in rats.
Specifications
CAS number
2253745-70-7
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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5-Butyl-4-phenyl-6-[4-(phenylmethoxy)phenyl]-2-pyrimidinamine
31337-1
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5-Butyl-4-phenyl-6-[4-(phenylmethoxy)phenyl]-2-pyrimidinamine
31337-1
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