Product description
1,2,3,4-Tetrahydro-B-carboline is a serotonin reuptake inhibitor (IC50 = 7.4 µM in rat brain homogenates) and metabolite of tryptamine (Item No. 20995).{58142} In vivo, 1,2,3,4-tetrahydro-B-carboline (20 and 40 µg/animal, i.c.v.) reduces serotonin levels in rat forebrain. It induces serotonin-mediated hyperactivity syndrome (HHS) in rats (ED50 = 48 mg/kg).{58143} 1,2,3,4-Tetrahydro-B-carboline (6.25-75 mg/kg) also reduces acetic acid-induced writhing in rats.{58144}
Specifications
CAS number
16502-01-5
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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