Product description
(Des-Arg9)-Bradykinin is an active metabolite of the endogenous vasodilator bradykinin (Item No. 37408) and a peptide agonist of the bradykinin B1 receptor.{49599,59178} It binds to bradykinin B1 and B2 receptors (Kis = 1.93 and 8.1 µM, respectively).{49601} (Des-Arg9)-Bradykinin is formed via carboxypeptidase-mediated cleavage of the bradykinin C-terminal arginine residue in plasma and tissues.{59178} It induces relaxation of precontracted isolated endothelium-denuded dog renal artery strips (pD2 = 8.6).{49603} (Des-Arg9)-Bradykinin decreases blood pressure in LPS-treated rabbits in a dose-dependent manner.{49600}
Specifications
CAS number
15958-92-6
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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