Product description
666-15 is an inhibitor of gene transcription mediated by cAMP-response-element-binding protein (CREB; IC50 = 81 nM in a cell-based reporter assay).{56180} It inhibits the growth of A549, MCF-7, MDA-MB-231, and MDA-MB-468 cells (GI50s = 0.47, 0.31, 0.073, and 0.046 ?M, respectively). 666-15 (10 mg/kg per day, five days per week) reduces tumor growth in an MDA-MB-468 mouse xenograft model.
Specifications
CAS number
1433286-70-4
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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