4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate.{24622,54088,54089,54090,54091} It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds.{24622,54088,54089} It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib (Item No. 10483), with antiproliferative activity.{54090,54091}