Liquiritin is a flavonoid that has been found in Glycyrrhiza and has diverse biological activities.{53639,53640,53641} It inhibits corticosterone-induced apoptosis in PC12 cells when used at concentrations of 1 and 2 mg/ml.{53639} Liquiritin (120 mg/kg) reduces spinal cord levels of IL-1B, IL-6, and TNF-a and alleviates mechanical and cold allodynia, as well as thermal hyperalgesia, in a mouse model of neuropathic pain induced by chronic constriction injury (CCI) of the sciatic nerve.{53640} It decreases the viability of SiHa, CaSki, and HeLa cervical cancer cells and inhibits migration and invasion of SiHa cells in vitro when used at concentrations of 40, 60, and 80 ?M.{53641} Liquiritin (10, 20, and 30 mg/kg) reduces tumor growth in a SiHa mouse xenograft model.
5 mg
CAS number
Cayman Chemical
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