Erythrodiol

Erythrodiol is a triterpene that has been found in olive oil and has diverse biological activities.{46856,46857,46858,46859} It induces relaxation of isolated rat aortic rings precontracted with phenylephrine (EC50 = 3.38 µM).{46856} Erythrodiol inhibits the growth of HT-29 adenocarcinoma cells (EC50 = 48.8 µM).{46857} It induces production of reactive oxygen species (ROS) and apoptosis in MCF-7 cells when used at a concentration of 100 µM.{46858} Topical administration of erythrodiol (0.5 mg/ear) reduces ear edema and myeloperoxidase (MPO) activity induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice.{46859}