4-Hydroxyhippuric Acid is a dihydroxy phenolic acid inhibitor of organic anion transporter 1 (OAT1; IC50 = 25 uM in opossum kidney cells).{48924} It increases the production of free radicals in opossum kidney cells expressing human OAT1. 4-Hydroxyhippuric Acid reduces the secretion of TNF-a, but not IL-1B or IL-6, in isolated human peripheral blood mononuclear cells (PBMCs) stimulated with LPS by 30.4% when used at a concentration of 1 uM.{48925}
100 mg
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Cayman Chemical
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