Product description
Australine is a pyrrolizidine alkaloid originally isolated from C. australe that has enzyme inhibitory activities.{54015,54016,54017} It is an inhibitor of glucoamylase (IC50 = 5.8 µM) that also inhibits glucosidase I, sucrase, maltase, and A. niger a-glucosidase (IC50s = 20, 28, 35, and 28 µM, respectively).{54016,54017} Australine is selective for these enzymes over glucosidase II, a- and B-mannosidase, and a- and B-galactosidase up to 500 µM, B-glucosidase, with only 5% inhibition at 66 µM, as well as isomaltase and trehalase (IC50 = 97 and 160 µM, respectively). Australine (500 µg/ml) inhibits glycoprotein processing of viral glycoproteins in influenza virus-infected MDCK cells and induces the accumulation of glycoproteins.{54016}
Specifications
CAS number
186766-07-4
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

Order your product by email

Productname

Australine (hydrochloride)

30051-1

By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


Request a sample

Productname

Australine (hydrochloride)

30051-1

By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


Organization information

*Required fields


Are you looking for specific products, alternatives or documentation?