C12 1-Deoxyceramide (m18:1/12:0) is a medium-chain atypical ceramide containing a 1-deoxysphingosine (m18:1(4E)) (Item No. 24687) backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.{40307,42289}