Legenda image
Surface staining of CD105 on Huvec cells with anti-CD105 (MEM-229) PE.
Product description
CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.
Specifications
Applications
FC
Host
Mouse
Clonality
Monoclonal
Clone
MEM-229
Isotype
Mouse IgG2a
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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PE Conjugated, Anti-CD105 / Endoglin Monoclonal Antibody (Clone:MEM-229)

30-2239

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PE Conjugated, Anti-CD105 / Endoglin Monoclonal Antibody (Clone:MEM-229)

30-2239

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