Legenda image
Surface staining of murine monocytes using anti-CD11a monoclonal antibody (clone M17/4) FITC.
Product description
CD11a (LFA-1 alpha) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. LFA-1 is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of LFA-1 to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3. LFA-1 is thus involved in interaction of various immune cells and in their tissue-specific settlement, but participates also in control of cell differentiation and proliferation and of T-cell effector functions.
Specifications
Applications
FC
Host
Rat
Clonality
Monoclonal
Clone
M17/4
Isotype
Rat IgG2a
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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FITC Conjugated, Anti-CD11a / LFA-1 alpha chain Monoclonal Antibody (Clone:M17/4)

30-2055

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FITC Conjugated, Anti-CD11a / LFA-1 alpha chain Monoclonal Antibody (Clone:M17/4)

30-2055

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